Non-Insulin Meds for DM2
First Line – Start with this.
MOA: inhibits gluconeogenesis
Weight loss, decreased mortality, decreased CV events. Because of this, continue even when insulin-dependent.
AE: GI. Take with meals.
CI in men with Cr >1.5 or women with Cr >1.4, or GFR<30.
Second Line – Add to Metformin if no improvement in A1C in 3 months. Can…
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